PDZ: A Sequence-based Computational Approach to Predicting PDZ Domain-Peptide Interactions

• Last updated: March 20, 2013

Introduction#

Welcome to our website! This is a webpage for our paper "A Sequence-based Computational Approach to Predicting PDZ Domain-Peptide Interactions". In this paper, we proposed a support vector machine-based predictor using dipeptide composition to qualitatively predict PDZ domain-peptide interaction with a high accuracy rate. Our method improves the prediction results significantly and it will highly benefit the research of drug target and drug design in identifying PDZ domain-ligand interactions. Pay attention to the users: You can use and redistribute the data and code if you accept GNU General Public License (GPL).

Any questions, please contact Dr. Zhi-Ping Liu by zpliuATsibs.ac.cn.

Reference#

• Nakariyakul S, Liu ZP and Chen L. A Sequence-based Computational Approach to Predicting PDZ Domain-Peptide Interactions. in submission.

Source code:#

• ModifiedBIRS.zip